4S)-3-(6-bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester_ Kain Industrial Additives

Background and overview[1] (1R,3S,4S)-3-(6-bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester can Harvoni is used as an intermediate in pharmaceutical synthesis, such as the preparation of a two-combination combination of the new antiviral NS5A inhibitor Ledipasvir (GS5885) and the NS5B blocker Sofosbuvir. It is a blockbuster hepatitis C treatment drug approved by Gilead in December 2013. Harvoni is the first all-oral anti-HCV regimen approved for the treatment of genotype 1…