Function and preparation method of 2,4,6-triphenoxy-1,3,5-triazine_Kain Industrial Additive
Background and overview[1][2] Also called 2,4,6-triphenol-1,3,5-s-triazine. Belongs to a class of small molecules, branched and polymer materials containing special triazine units, which are used in organic electroluminescence, organic field effect tubes, organic solar cells, nonlinear optics, biosensing, organic light storage and Organic lasers and other fields have a wide range of applications. Organic optoelectronic functional materials such as liquid crystals, nonlinear optics and electroluminescence derived from…
How to prepare 3,4,5,6-tetrafluorophthalic acid_Kain Industrial Additive
Background and overview[1][2] 3,4,5,6-Tetrafluorophthalic acid, pure product is a white granular crystalline solid. This compound is mainly used as pharmaceutical intermediates and intermediates for the synthesis of fluorine-containing aromatic chemicals. It is a key intermediate for the preparation of ofloxacin and other fluoroquinolone antibiotics. CN102627553A, CN86106151, US5047553 and “Improvement of the Synthesis Process of Tetrafluorophthalic Acid” are described in Chinese Journal of Medicinal Chemistry, Volume 19,…
Preparation of 3,4,5-trimethoxybromobenzene_Kain Industrial Additive
Background and overview[1] 3,4,5-Trimethoxybromobenzene can be used as a pharmaceutical synthesis intermediate. It can be prepared by the reaction of 5-bromo-1,2,3 trihydroxybenzene and dimethyl sulfate, or it can also be prepared from 4-bromo-2 , 6-dimethoxyphenol was prepared as the reaction raw material. Preparation[1-2] Option 1, Cool the mixture of 5-bromo-1,2,3 trihydroxybenzene (1.3g, 5.63mmol), 1M NaOH (14mL) and dimethyl sulfate (800μL, add 16.89mmol) to 10°C. The mixture…
Production method and device of 2,4,5-trichloroaniline_Kain Industrial Additive
Background and overview[1] 2,4,5-Trichloroaniline is a poison that can spontaneously ignite. It also has the function of supporting combustion and can also be used as a dye intermediate. It is slightly soluble in petroleum ether and easily soluble in ethanol and carbon disulfide. During the production and preparation process, it needs to be in a cool and ventilated environment, and workers must wear protective clothing to…
Preparation of 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one_Kain Industrial Additive
Background and Overview[1] 3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. Benazepril hydrochloride is a first-line antihypertensive drug recommended by the World Health Organization. It is a chiral drug with good clinical efficacy, high safety and few side effects among the current international angiotensin-converting enzyme inhibitor antihypertensive drugs. . 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one Preparation[2] The synthesis methods reported in the literature mainly include: 1. Using a composite…
Application of 2-(2-difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane_Kain Industrial Additive
Background and Overview 2-(2-Difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane is an organic intermediate commonly used in metal catalysis coupling reaction, Application examples[1-2] Report 1, CN201780052527.0 reported that 2-(2-difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane can be used to synthesize compound 6-amino -N-(5-chloro-6-(2-(difluoromethyl)phenyl)pyridin-2-yl)pyridine-2-sulfonamide. This compound is a CF transmembrane conductance regulator (CFTR) corrector. Cystic fibrosis (CF) is caused by loss-of-function mutations in the CF transmembrane conductance regulator (CFTR) protein, which is a cAMP-regulated chloride channel that is mainly…
Preparation and application of 2,4,5,6-tetrafluoroisophthalonitrile_Kain Industrial Additive
Background and overview[1] 2,4,5,6-tetrafluoroisophthalonitrile can be used as a pharmaceutical synthesis intermediate, such as the preparation of dichloruron, which is an insect growth regulator, and the better representative is dichloruron. . Chemuron has the following advantages: 1. Unique mechanism of action, low toxicity to beneficial organisms, easy to degrade, high selectivity, relatively safe, and is an insect growth regulator. 2. High biological activity and low effective…
2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS: 852227-95-3Chinese name: 4-[3-(4,4,5, 5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenyl Pinacol borate2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2 -DioxaborolaneEnglish name: 4-[3-(4,4,5, 5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenylboronic acid pinacol ester 2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine
CAS: 852227-95-3Chinese name: 4-[3-(4,4,5, 5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenyl Pinacol borate2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2 -DioxaborolaneEnglish name: 4-[3-(4,4,5, 5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenylboronic acid pinacol ester 2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
n,n’-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine and morpholine-2,4,6-trichloro-1,3, Methylated polymer of 5-triazine
CAS: 193098-40-7Chinese name: UV absorber uv3529 n,n’-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexamethylenediamine and morpholine-2,4,6-tri Methylated polymers of chloro-1,3,5-triazines