Preparation of 2,3,4,5-tetrahydro-1H-benzo[d]azepine_Kain Industrial Additive
Background and overview[1][2] 2,3,4,5-Tetrahydro-1H-benzo[d]azepine (hydrochloride), CAS number 4424-20-8, chemical formula C10H13N. Molecular weight 147.21700. Density 0.981g/cm3, boiling point 258.8ºC at 760 mmHg, flash point 114.9ºC, refractive index 1.53. 2,3,4,5-Tetrahydro-1H-benzo[d]azepine (hydrochloride) is available Used as pharmaceutical and chemical synthesis intermediates. If 2,3,4,5-tetrahydro-1H-benzo[d]azepine (hydrochloride) is inhaled, move the patient to fresh air; in case of skin contact, remove contaminated clothing and use Rinse skin thoroughly with soap and…
Application of α-bromo-2,3,4,5,6-pentafluorotoluene_Kain Industrial Additive
Background and Overview α-Bromo-2,3,4,5,6-pentafluorotoluene is a benzene derivative that can be used as a derivatization reagent for gas chromatography analysis of multifunctional thiols, and can also be used to prepare pentafluorobenzene ester. Apply[1] α-Bromo-2,3,4,5,6-pentafluorotoluene can be used to prepare trithiocarbonate-bis(pentafluorobenzyl)ester: Reversible addition-fragmentation chain transfer polymerization (RAFT polymerization) is a typical controllable and living radical polymerization method. In recent years, RAFT polymerization has become an important method…
Application of 2,3,4,6-Tetrachlorophenol_Kain Industrial Additive
Background and overview[1] Arsenic atomic absorption standard, also known as 2,3,4,6-tetrachlorophenol in Chinese, can be used as a pharmaceutical synthesis intermediate. Chlorophenols are a typical class of “three-causing (carcinogenic, teratogenic, mutagenic)” organic pollutants and are widely used in the production of preservatives, dyes, herbicides and pesticides. At the same time, chlorophenols by-products may also be produced during waste incineration, pulp bleaching, and drinking water chlorination and…
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Preparation method of 1,3,5-trimethoxybenzene_Kain Industrial Additive
Background and overview[1] 1.3.5-Trimethoxybenzene is a white crystalline powder, insoluble in water, and an important organic synthesis intermediate. It is mainly used in the fields of pharmaceutical manufacturing and pesticide synthesis. It is a new dilation drug for peripheral vascular disorders. An important raw material of Bullomedil. 1.3.5-Trimethoxybenzene was originally developed by a German company. Hu Yimin and others from the Institute of Organic Chemistry of…
Application of 4-cyanomethyl-2,3,5,6-tetrafluorobenzonitrile_Kain Industrial Additive
Overview[1][2] 4-Cyanomethyl-2,3,5,6-tetrafluorobenzonitrile is a photochemical intermediate that can be prepared from hexafluorobenzonitrile in one step and can be used to synthesize luminescent materials. Preparation[1] Add hexafluorobenzonitrile (1.93g, 10mmol), ethyl cyanoacetate (1.11g, 10mmol), potassium carbonate (1.67g, 12.1mmol), and 30mL of DMF into the reactor, and stir for 48 hours at room temperature. Distilled water and acetic acid were added to terminate the reaction, extracted with dichloromethane and…
Preparation of 2-benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine_Kain Industrial Additive
Background[1][2] 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly used in experiments Laboratory research and development process and chemical and pharmaceutical synthesis process. Preparation[1] 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine is prepared as follows: Step 1: N-ethoxy-3-methylpyridinium iodide: Add 3-methylpyridine-N-oxide (50.00g, 458mmol) and anhydrous dichloromethane (90mL) to the round-bottomed flask. Ethyl iodide (715.57g, 4587mmol) was added and stirred at room temperature overnight. After the…
Application of 1-acetoxy-2,3,5-tribenzoyloxy-1-beta-D-ribofuranose_Kain Industrial Additive
Background and overview[1] Among chemical drugs, nucleosides and their derivatives with therapeutic effects play a very important role, and their numbers are growing rapidly. Among them, 1-acetoxy-2,3,5-trityl Acyloxy-1-beta-D-ribofuranose is a key intermediate in the synthesis of nucleosides and their derivatives. The chemistry and medicinal chemistry of nucleoside compounds is an emerging research field at home and abroad. Nucleosides or nucleotide analogs with antiviral activity are commonly…
Preparation of 2,4,6-tris(4-aminophenyl)-1,3,5-triazine_Kain Industrial Additive
Background and overview[1] 2,4,6-Tris(4-aminophenyl)-1,3,5-triazine is a heterocyclic organic compound that can be used as a pharmaceutical synthesis intermediate. Preparation[1] Preparation of 2,4,6-tris(4-aminophenyl)-1,3,5-triazine: Method 1: Add 1.18g (10mmol) of p-aminobenzonitrile to a 50mL four-necked flask, add 25mL of methylene chloride under magnetic stirring to dissolve it, and slowly add 4mL (45mmol) of trifluoromethanesulfonate dropwise in an ice bath. Acid, add N2 to protect the reaction for 24…
Function and preparation method of 2,4,6-triphenoxy-1,3,5-triazine_Kain Industrial Additive
Background and overview[1][2] Also called 2,4,6-triphenol-1,3,5-s-triazine. Belongs to a class of small molecules, branched and polymer materials containing special triazine units, which are used in organic electroluminescence, organic field effect tubes, organic solar cells, nonlinear optics, biosensing, organic light storage and Organic lasers and other fields have a wide range of applications. Organic optoelectronic functional materials such as liquid crystals, nonlinear optics and electroluminescence derived from…
Preparation of N,N’,N”-triphenyl-1,3,5-phenyltriamine_Kain Industrial Additive
Background and overview[1] During the use of lubricating oil, oxidation reactions will occur under the influence of air, water, metal, etc., especially in high-temperature working environments, it will quickly oxidize and deteriorate, and lose its own functions. Therefore, antioxidants must be added to prevent the rapid oxidation of the lubricating oil and extend the working life of the lubricating oil. Antioxidants are important additives that can…
